Clinical Trial SetbacksCohort 2 demonstrated limited anti-tumor activity, with all patients progressing after the first or second cycle of treatment.
Competitive ChallengesWith key near-term catalysts passed and a backdrop of increasing competition, the rating is lowered to Neutral from Buy.
Efficacy ConcernsThe efficacy of Pb-212-VMT-α-NET fell short of the high expectations that were established with the asset's performance in the investigator initiated trial in India.