Clinical Program RisksBoth ongoing clinical programs, BDC-3042 and the next-generation ISAC candidate, are considered high-risk due to their novelty and early stage of development.
Efficacy ConcernsThe initial dose-expansion cohorts of BDC-1001 failed to meet Bolt’s pre-specified 30% overall response rate efficacy threshold.
Strategic And Management ChangesThe company has discontinued their lead program, BDC-1001, and is undergoing strategic and management changes.