Record Orladeo Revenue Growth
Orladeo revenue grew by 34% year-over-year. The company added as many patients in 2024 as in the first year of launch, reflecting excellent execution by the commercial team.
Strong Financial Performance
BioCryst generated a non-GAAP operating profit of over $60 million, which is three times larger than planned. Total revenue for 2024 was $450.7 million.
Pipeline Advancements
Progress in clinical trials for BCX1775 in Netherton syndrome and Avoralstat for diabetic macular edema (DME). Plans to file NDA for Orladeo in pediatric use this year.
Positive Impact of Inflation Reduction Act
Higher percentage of Medicare patients on Orladeo can afford co-payments, increasing revenue guidance for Orladeo to $535 million to $550 million for 2025.
Strong Retention and Prescriber Momentum
97% of HAE treaters are considering prescribing Orladeo, with 59% extremely likely to prescribe to more patients. Positive real-world evidence supporting Orladeo's efficacy.