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Zelira Therapeutics Ltd. (AU:ZLD)
:ZLD
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Zelira Therapeutics (ZLD) AI Stock Analysis

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AU:ZLD

Zelira Therapeutics

(OTC:ZLD)

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Underperform 39 (OpenAI - 4o)
Rating:39Underperform
Price Target:
AU$0.50
▲(42.86% Upside)
Zelira Therapeutics' overall stock score is primarily driven by its severe financial difficulties, including significant revenue decline and negative equity. Technical analysis indicates weak momentum, and valuation metrics reflect unprofitability. The absence of earnings call data and corporate events limits additional insights.

Zelira Therapeutics (ZLD) vs. iShares MSCI Australia ETF (EWA)

Zelira Therapeutics Business Overview & Revenue Model

Company DescriptionZelira Therapeutics (ZLD) is a biopharmaceutical company focused on the development and commercialization of innovative cannabinoid-based therapeutics. Operating primarily in the healthcare sector, Zelira aims to address various health conditions, including chronic pain, sleep disorders, and other serious ailments. The company leverages its proprietary formulations and clinical research to create products that are designed to improve patient outcomes and quality of life.
How the Company Makes MoneyZelira Therapeutics generates revenue primarily through the sale of its proprietary cannabinoid-based products, which are marketed to both consumers and healthcare providers. The company also engages in partnerships and collaborations with other pharmaceutical companies and research institutions to develop new therapies and expand its product portfolio. Additionally, Zelira may receive funding through grants, licensing agreements, and joint ventures that support its research and development efforts. These strategic partnerships often include milestone payments and royalties, further contributing to the company's earnings.

Zelira Therapeutics Financial Statement Overview

Summary
Zelira Therapeutics is facing severe financial challenges with significant revenue decline, negative margins, and negative equity. The company shows substantial losses across income, balance sheet, and cash flow statements, indicating critical financial instability.
Income Statement
10
Very Negative
Zelira Therapeutics has experienced significant revenue decline, with a revenue growth rate of -98.4% in the most recent year. The company has negative gross profit, net profit, and EBIT margins, indicating substantial losses. These metrics reflect severe financial challenges and a lack of profitability.
Balance Sheet
15
Very Negative
The balance sheet shows negative stockholders' equity, which is concerning. The debt-to-equity ratio is negative due to negative equity, and the return on equity is positive but misleading due to negative equity. The equity ratio is also negative, indicating financial instability.
Cash Flow
20
Very Negative
The company has negative operating and free cash flows, with a slight improvement in free cash flow growth. However, the operating cash flow to net income ratio is negative, reflecting ongoing cash flow challenges. The free cash flow to net income ratio is 1.0, indicating that all net income is being used for free cash flow, but this is due to both being negative.
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue655.00656.0094.95K301.12K1.54M663.32K
Gross Profit-802.95K-802.95K10.28K-3.22M-5.72M-39.16K
EBITDA-4.17M-4.17M-36.44M-6.79M-13.06M-9.41M
Net Income-3.63M-3.63M-36.57M-5.57M-11.95M-8.55M
Balance Sheet
Total Assets1.30M1.30M5.18M33.89M37.70M39.37M
Cash, Cash Equivalents and Short-Term Investments5.66K5.66K586.16K146.21K2.75M4.97M
Total Debt2.14M2.14M5.95M437.90K500.91K551.08K
Total Liabilities5.59M5.59M9.36M2.18M2.01M1.54M
Stockholders Equity-4.46M-4.46M-4.51M31.80M35.20M37.83M
Cash Flow
Free Cash Flow-4.91M-4.91M-4.39M-7.25M-9.43M-8.62M
Operating Cash Flow-4.91M-4.91M-4.39M-7.25M-9.43M-8.62M
Investing Cash Flow1.15M1.15M919.74K2.83M-207.78K1.38M
Financing Cash Flow3.19M3.19M3.92M1.77M7.10M10.53M

Zelira Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.35
Price Trends
50DMA
0.38
Negative
100DMA
0.40
Negative
200DMA
0.44
Negative
Market Momentum
MACD
-0.01
Positive
RSI
41.33
Neutral
STOCH
12.70
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AU:ZLD, the sentiment is Negative. The current price of 0.35 is below the 20-day moving average (MA) of 0.36, below the 50-day MA of 0.38, and below the 200-day MA of 0.44, indicating a bearish trend. The MACD of -0.01 indicates Positive momentum. The RSI at 41.33 is Neutral, neither overbought nor oversold. The STOCH value of 12.70 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for AU:ZLD.

Zelira Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
AU$9.77M-20.63-8.72%71.10%
AU$44.90M-10.71-16.65%-672.73%
$7.86B-0.30-43.30%2.27%22.53%-2.21%
AU$14.28M-143.71%306.88%
AU$3.93M-99.31%90.20%
AU$6.62M-628.72%31.87%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AU:ZLD
Zelira Therapeutics
0.33
-0.37
-52.86%
AU:IXC
Invex Therapeutics Ltd.
0.12
0.03
33.33%
AU:CMB
Regeneus Ltd.
0.52
0.11
26.83%
AU:AVE
Avecho Biotechnology Limited
AU:1AD
AdAlta Ltd.
0.01
-0.01
-50.00%
AU:NSB
Neuroscientific Biopharmaceuticals Ltd.
0.10
0.06
150.00%

Zelira Therapeutics Corporate Events

Zelira Therapeutics Secures R&D Loan and Advances Clinical Trials
Oct 27, 2025

Zelira Therapeutics has announced a non-dilutive R&D loan facility secured against its anticipated R&D tax incentive rebate for FY25, which will be used to advance the HOPE® SPV clinical trial and general working capital. Additionally, the company’s directors have provided unsecured loan notes to support operations. The company is making significant progress in its FDA program for the HOPE® clinical trial, with plans to launch Phase 1 trials for its HOPE® 1 Phelan McDermid Syndrome program. This development is part of Zelira’s strategy to bring effective cannabinoid-based therapies to market, targeting ultra-rare genetic conditions and improving patient outcomes.

The most recent analyst rating on (AU:ZLD) stock is a Hold with a A$0.50 price target. To see the full list of analyst forecasts on Zelira Therapeutics stock, see the AU:ZLD Stock Forecast page.

Zelira Therapeutics Announces Cessation of Securities
Oct 22, 2025

Zelira Therapeutics Limited announced the cessation of 125,723 securities due to the expiry of options or other convertible securities without exercise or conversion. This development may impact the company’s capital structure and could influence investor perceptions and market positioning as the company continues its strategic initiatives.

The most recent analyst rating on (AU:ZLD) stock is a Sell with a A$0.50 price target. To see the full list of analyst forecasts on Zelira Therapeutics stock, see the AU:ZLD Stock Forecast page.

Zelira Therapeutics Announces Key Resolutions for Upcoming AGM
Oct 20, 2025

Zelira Therapeutics has announced its upcoming Annual General Meeting, scheduled for November 19, 2025, which will be held both virtually and physically in Perth. Key agenda items include the adoption of the remuneration report, re-election of director Greg Blake, and approval of convertible notes for Dr. Oludare Odumosu and Dr. Donna Gentile O’Donnell. Additionally, the company seeks to renew its proportional takeover provisions in the constitution. These resolutions, if passed, could impact the company’s governance and financial strategies, potentially influencing shareholder value and market perception.

The most recent analyst rating on (AU:ZLD) stock is a Sell with a A$0.50 price target. To see the full list of analyst forecasts on Zelira Therapeutics stock, see the AU:ZLD Stock Forecast page.

Zelira Therapeutics Releases 2025 Corporate Governance Statement
Sep 26, 2025

Zelira Therapeutics has released its corporate governance statement for the financial year ending June 30, 2025, which is available on their website. The statement outlines the company’s adherence to ASX Corporate Governance Council’s principles, detailing the roles and responsibilities of the board and management, and the processes for director appointments and accountability, thereby reinforcing its commitment to transparency and effective governance practices.

The most recent analyst rating on (AU:ZLD) stock is a Sell with a A$0.50 price target. To see the full list of analyst forecasts on Zelira Therapeutics stock, see the AU:ZLD Stock Forecast page.

Zelira Therapeutics Secures Director Loans to Enhance Working Capital
Sep 16, 2025

Zelira Therapeutics announced that its Managing Director, Dr. Oludare Odumosu, and Non-Executive Director, Dr. Donna Gentile O’Donnell, will provide a total of USD$150,000 in unsecured loan notes to the company. These funds will be used for general working capital purposes. The loan notes, subject to shareholder approval, may be converted into shares at a premium price, reflecting favorable terms for the company amidst current market conditions. This strategic financial move is expected to bolster Zelira’s operational capabilities and strengthen its market position.

The most recent analyst rating on (AU:ZLD) stock is a Sell with a A$0.50 price target. To see the full list of analyst forecasts on Zelira Therapeutics stock, see the AU:ZLD Stock Forecast page.

Zelira Therapeutics Reports Increased Loss Amidst Clinical Progress and Expansion Plans
Aug 29, 2025

Zelira Therapeutics reported a significant increase in net loss for the year ended June 2025, despite making progress in clinical validation and development. The company has established a special purpose vehicle to conduct FDA trials for its HOPE® 1 product and has demonstrated the efficacy of its treatments in a study comparing them to Lyrica®. Zelira’s proprietary formulations under the HOPE® brand are generating revenue in multiple regions, and the company plans to expand its ZENIVOL® product into Germany. Additionally, Zelira is exploring commercialization opportunities for its Zyraydi™ technology and continues to generate revenue from its OTC products.

The most recent analyst rating on (AU:ZLD) stock is a Sell with a A$0.50 price target. To see the full list of analyst forecasts on Zelira Therapeutics stock, see the AU:ZLD Stock Forecast page.

Zelira Therapeutics Advances Diabetic Neuropathy Study and Strengthens Financial Position
Jul 30, 2025

Zelira Therapeutics has announced significant progress in its diabetic neuropathy study, with its proprietary cannabinoid-based therapy, ZLT-L-007, outperforming Lyrica® in reducing pain and improving quality of life for patients. This advancement, alongside the conversion of US$3.25 million in convertible notes into equity, strengthens Zelira’s financial position and supports its clinical and regulatory development efforts. The company is poised to continue its momentum with upcoming FDA trials and the optimization of its Zyraydi™ technology, aiming to unlock value across its product lines.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 29, 2025