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Arcturus Therapeutics (ARCT)
NASDAQ:ARCT
US Market

Arcturus Therapeutics (ARCT) AI Stock Analysis

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Arcturus Therapeutics

(NASDAQ:ARCT)

46Neutral
Arcturus Therapeutics has a challenging financial outlook with declining revenues and increased losses impacting profitability. While the company has a strong cash position and notable achievements like the European approval of KOSTAIVE, negative technical indicators and valuation challenges present significant hurdles. The mixed sentiment from the earnings call further impacts the overall score.
Positive Factors
Financial Support
The ARCT-2304 mRNA vaccine candidate against the H5N1 virus is fully-funded by BARDA, providing financial support for its development.
Regulatory Approvals
The company's proprietary STARR and LUNAR technologies have received recent regulatory approvals in Japan and the EU.
Negative Factors
Revenue Decline
FY24 revenue of $152mm was below expectations, representing a ~9% year-over-year decline mainly due to lower CSL milestones.
Revenue Reduction
Collaborative revenue for Arcturus in 2025 is reduced from $138.4 million to $65 million reflecting the winding down of Kostaive clinical development efforts.

Arcturus Therapeutics (ARCT) vs. S&P 500 (SPY)

Arcturus Therapeutics Business Overview & Revenue Model

Company DescriptionArcturus Therapeutics (ARCT) is a biotechnology company specializing in the development of RNA-based medicines using its proprietary technologies. The company focuses on leveraging its innovative platforms to create therapies for rare diseases and infectious diseases. Arcturus' core products include mRNA therapeutics and vaccines, designed to address unmet medical needs in a variety of therapeutic areas.
How the Company Makes MoneyArcturus Therapeutics generates revenue primarily through strategic partnerships and collaborations with other pharmaceutical companies, leveraging its proprietary RNA-based technologies. These partnerships often involve upfront payments, milestone payments, and potential royalties on product sales. Additionally, Arcturus may engage in licensing agreements, allowing other companies to use its technology in exchange for fees, contributing further to its revenue streams. The company's ability to monetize its innovative platforms and demonstrate clinical success in its development programs are key factors influencing its earnings.

Arcturus Therapeutics Financial Statement Overview

Summary
Arcturus Therapeutics is facing a challenging financial landscape with volatile revenue growth and persistent losses impacting profitability metrics. While the company benefits from a strong cash position and moderate leverage, its inconsistent cash flow performance and negative net income indicate areas that require strategic improvement to achieve financial stability.
Income Statement
45
Neutral
Arcturus Therapeutics has shown volatile revenue growth with a recent decline from 2023 to 2024. The company has maintained a high gross profit margin, but the net profit margin remains negative due to persistent losses. The EBIT and EBITDA margins have also deteriorated, reflecting operational challenges.
Balance Sheet
55
Neutral
The balance sheet displays a strong cash position and a negative net debt, indicating significant cash reserves. However, the debt-to-equity ratio has increased slightly, suggesting a moderate level of leverage. The equity ratio remains stable, reflecting a solid capital structure.
Cash Flow
40
Negative
The operating cash flow has been inconsistent, with a significant drop in 2024. Free cash flow has also been volatile and negative, pointing to challenges in generating cash from operations. The company needs to improve its cash flow management to support growth.
Breakdown
Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
152.31M157.75M205.75M12.36M9.54M
Gross Profit
152.31M154.79M62.70M-159.50M-46.41M
EBIT
-95.67M-78.20M12.18M-202.85M-71.52M
EBITDA
-77.40M-24.17M13.70M-201.66M-70.64M
Net Income Common Stockholders
-80.94M-29.73M9.35M-206.86M-71.36M
Balance SheetCash, Cash Equivalents and Short-Term Investments
237.03M292.00M391.88M370.49M462.89M
Total Assets
344.07M429.40M450.39M392.81M476.46M
Total Debt
25.00M30.22M90.87M67.61M17.87M
Net Debt
-212.03M-261.79M-301.01M-302.88M-445.02M
Total Liabilities
103.09M150.89M180.07M164.60M79.90M
Stockholders Equity
240.98M278.51M270.31M228.21M396.55M
Cash FlowFree Cash Flow
-60.40M-21.00M24.27M-138.45M-44.60M
Operating Cash Flow
-59.75M-18.10M31.99M-135.04M-42.86M
Investing Cash Flow
-648.00K-2.90M-7.73M-3.41M-1.74M
Financing Cash Flow
5.42M-24.09M-2.86M48.02M436.14M

Arcturus Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price9.08
Price Trends
50DMA
14.71
Negative
100DMA
16.06
Negative
200DMA
18.77
Negative
Market Momentum
MACD
-1.37
Positive
RSI
22.40
Positive
STOCH
4.55
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ARCT, the sentiment is Negative. The current price of 9.08 is below the 20-day moving average (MA) of 12.10, below the 50-day MA of 14.71, and below the 200-day MA of 18.77, indicating a bearish trend. The MACD of -1.37 indicates Positive momentum. The RSI at 22.40 is Positive, neither overbought nor oversold. The STOCH value of 4.55 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for ARCT.

Arcturus Therapeutics Risk Analysis

Arcturus Therapeutics disclosed 60 risk factors in its most recent earnings report. Arcturus Therapeutics reported the most risks in the “Finance & Corporate” category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Arcturus Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (48)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
PFPFE
68
Neutral
$130.27B16.309.05%7.36%8.77%272.80%
54
Neutral
$21.13B-3.38%-27.64%-172.62%
48
Neutral
$9.69B-28.77%-52.75%25.00%
48
Neutral
$6.35B1.19-46.87%2.63%17.16%1.34%
46
Neutral
$247.06M-31.16%-13.98%-200.43%
39
Underperform
$1.00B30.06%-30.65%77.62%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ARCT
Arcturus Therapeutics
9.08
-22.58
-71.32%
NVAX
Novavax
6.54
2.12
47.96%
PFE
Pfizer
22.63
-2.57
-10.20%
MRNA
Moderna
25.64
-85.96
-77.03%
BNTX
BioNTech SE
86.82
-3.23
-3.59%

Arcturus Therapeutics Earnings Call Summary

Earnings Call Date: Mar 6, 2025 | % Change Since: -43.14% | Next Earnings Date: May 12, 2025
Earnings Call Sentiment Neutral
The earnings call presented a mixed outlook for Arcturus Therapeutics. While there were significant achievements such as the European approval of KOSTAIVE and progress in various clinical programs, these were offset by financial challenges including decreased revenue and increased net loss. The company's strong cash position and expected cash runway provide some reassurance.
Highlights
European Commission Approval for KOSTAIVE
Arcturus Therapeutics received European Commission approval for KOSTAIVE, the world's first approved self-amplifying mRNA COVID-19 vaccine, covering all 27 EU member states and 3 additional European economic area countries.
Significant Gross Profit from KOSTAIVE
Arcturus' share of gross profit from the sale of KOSTAIVE during Q4 2024 was approximately $28 million, which will offset development costs.
Initiation of Phase I Study for ARCT-2304
Initiated a Phase I study of ARCT-2304, a self-amplifying mRNA vaccine candidate for H5N1, fully funded by BARDA with interim data expected in the second half of 2025.
Continued Progress in Cystic Fibrosis Program
Dosed the first participant in a Phase II study of ARCT-032 for cystic fibrosis, with interim data expected by the end of Q2 2025.
Strong Cash Position
Cash and cash equivalents were $293.9 million as of December 31, 2024, with a cash runway expected until the end of Q1 2027.
Lowlights
Decrease in Revenue
Revenues for the year ended 2024 decreased by $14.5 million to $152.3 million compared to 2023, primarily due to lower milestone achievements from the CSL agreement.
Increased Net Loss
Reported a net loss of approximately $80.9 million for the year ended 2024, compared to a net loss of $29.7 million in 2023.
Increased Operating Expenses
Total operating expenses for 2024 increased to $248 million from $245 million in 2023, driven by higher clinical trial costs.
Company Guidance
During the Arcturus Therapeutics Fourth and Full Year 2024 Earnings Call, several key metrics and updates were shared. For the fiscal year ending December 31, 2024, the company reported revenues of $152.3 million, a decrease from $166.8 million in 2023, largely due to lower milestone achievements from the CSL agreement. However, revenues for the fourth quarter of 2024 amounted to $22.8 million. Operating expenses for 2024 were $248 million, up slightly from $245 million in 2023, with research and development expenses rising to $195.2 million. The company reported a net loss of $80.9 million for 2024. Importantly, Arcturus achieved a significant milestone with the European Commission's approval of KOSTAIVE, the world's first approved self-amplifying mRNA COVID-19 vaccine, and recorded a $28 million gross profit share from its sale. The company anticipates continued revenue from ongoing clinical programs and maintains a strong cash position of $293.9 million as of December 31, 2024, supporting a cash runway extending to the end of Q1 2027. Additionally, Arcturus is progressing with its pipeline, including a Phase I study of ARCT-2304 for H5N1 influenza and a Phase II study for ARCT-032 in cystic fibrosis, with key data readouts expected in 2025.
Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.