Clinical ProgressAPR-1051 recently began enrollment in its Phase 1 ACESOT-1051 study, in patients with advanced solid tumors overexpressing Cyclin E, and other biomarkers predicted to be sensitive to WEE1 inhibition.
Financial StrengthThe company ended the quarter with $28.7 million in cash, which management believes should provide runway for all ongoing operations into 4Q25.
Safety ProfileAPR-1051 is a completely different molecule from other WEE1 inhibitors that have had toxicity issues, and the FDA has permitted the P1 to use continuous dosing based on preclinical data.