FILSPARI Approval and Market Expansion
FILSPARI received full approval for IgA nephropathy, leading to significant growth in net sales by more than 30% over the last quarter. The product's new label supports broader use in patients at risk of progression and has been launched in key European markets.
Strong Financial Performance
Net product sales for the third quarter of 2024 grew to $61 million, an increase of approximately 80% compared to the same period in 2023, driven by the ongoing U.S. launch of FILSPARI.
Positive Clinical Data and Regulatory Progress
New clinical data presented at ASN Kidney Week supports the efficacy of FILSPARI in reducing proteinuria and preserving kidney function. Additionally, an sNDA was submitted to modify liver monitoring frequency, potentially improving patient access.
PARASOL Initiative and FSGS Opportunity
Recommendations from the PARASOL group support a proteinuria-based endpoint for FSGS trials. Travere is preparing for a meeting with the FDA regarding an sNDA submission for sparsentan in FSGS.
Reduced Operating Expenses
Research and development expenses decreased from $60.6 million in Q3 2023 to $51.7 million in Q3 2024, reflecting restructuring efforts and reduced clinical expenses.