Clinical Development And PotentialExpectations are high for petosemtamab trials to yield positive outcomes, potentially leading to accelerated approval, driven by its promising performance in targeting LGR5-expressing cancers.
Efficacy Of PetosemtamabPetosemtamab demonstrates a significant advantage with a 36% overall response rate, notably higher than the typical 10% seen with cetuximab in head and neck squamous cell carcinoma.
Safety And Combination PotentialThe improved safety profile of petosemtamab supports its potential for combination with chemotherapy in colorectal cancer, enhancing its versatility as a treatment option.