Patient Pool LimitationPatients with 5 or more prior lines of therapy will be excluded from expansion, which may limit the patient pool.
Side Effect ManagementManagement is more concerned with decreasing dose delays rather than decreasing proteinuria events, indicating ongoing challenges with managing side effects.
Unclear Competitive ImpactThe reasons behind PFE’s decision to discontinue its B7-H4 program remain unclear, leading to caution about drawing conclusions regarding its implications for MRSN.