MRT-6160 Phase 1 Study Success
The Phase 1 SAD/MAD study of MRT-6160 in healthy volunteers showed dose-dependent VAV1 degradation exceeding 90%, with significant inhibition of cytokine secretion up to 99%, and was well tolerated.
Strategic Agreement with Novartis
Monte Rosa Therapeutics announced an exclusive strategic development agreement with Novartis for MRT-6160, aiming to accelerate and broaden its development.
NEK7 Program IND Submission On Track
NEK7 program is on track for an IND submission in the first half of the year, with promising preclinical data showing potent degradation of NEK7 and favorable safety profile.
Encouraging Data in Prostate Cancer
Initial data in the castration-resistant prostate cancer cohort showed one confirmed partial response and two stable diseases among three patients.
Strong Financial Position
Monte Rosa Therapeutics has a strong balance sheet with cash runway anticipated into 2028.