Clinical Trials FailureAbbVie disclosed that both of its registrational studies (EMPOWER 1&2) of emraclidine for schizophrenia failed to meet their primary endpoints.
Financial Guidance And Market ChallengesThe company lowered 2024 aesthetics guidance to $5.5bn from $5.7bn, reflecting challenges such as Juvederm's vulnerability to macroeconomic weakness due to its higher price point.
Sales Erosion And Patent ExpiryContinued headwinds of Humira patent expiry are expected to create a difficult near-term period for the company, coupled with the downside risk from lower Humira sales and loss of exclusivity in the US.