CUE-101 and Pembrolizumab Combination Shows Promising Results
CUE-101 in combination with Pembrolizumab shows an objective response rate (ORR) of 46% in patients with CPS ≥ 1, compared to the historical ORR of 19% with Pembrolizumab alone. The 12-month overall survival (OS) is 90% with a median OS of 21.8 months.
Strong Performance in Low CPS Score Patients
Patients with low CPS scores (1 to 19) showed an ORR of 50% with CUE-101 and Pembrolizumab, significantly higher than the historical 15% with Pembrolizumab alone.
CUE-401 Autoimmune Program Progress
CUE-401, in collaboration with ONO Pharmaceuticals, shows promising data in generating regulatory T cells and is moving towards lead candidate selection in Q1 2025.
Financial Strategy and Extended Runway
Through strategic measures, the company's runway is extended to mid-2025 while reducing annual cash burn from $40 million to $30 million.