Product EfficacyPatients not enriched with OncoSignature did not respond to ACR-368, suggesting the necessity of patient selection for effective treatment.
Product Information TransparencyThe company did not provide much detail into the OncoSignature diagnostic, limiting direct comparisons to other diagnostics.
Scientific UnderstandingWhile BOLD's focus on extra-chromosomal DNA is groundbreaking, the biological role of ecDNA is not fully understood, introducing inherent risks to their novel therapeutic approaches.