Clinical Trial SuccessSellas announced positive data from a P2a trial for selective CDK9 inhibitor SLS009 combined with the approved BTK inhibitor Brukinsa in relapsed/refractory diffuse large B-cell lymphoma, showing a 67% overall response rate, which is more than double that of zanubrutinib alone.
Pipeline ExpansionThere is potential for SLS009 in ASXL1-mutated solid tumors, which could attract partnership opportunities and expand its application beyond AML.
Regulatory ApprovalThe Independent Data Monitoring Committee recommended continuing the P3 REGAL study for Galipepimut-S in acute myeloid leukemia unmodified, indicating sufficient separation between trial arms to reach its primary endpoint.