Transformative Year for Vir Biotechnology
2024 was described as transformative, with significant strides made in oncology and infectious disease programs, positioning Vir Bio at the forefront of innovative therapies.
ECLIPSE Phase III Program Initiation
Preparations for the ECLIPSE Phase III program in hepatitis delta are underway, with initiation expected in the first half of the year. Regulatory designations received include U.S. FDA breakthrough therapy and Fast Track designation, as well as EMA PRIME designation and Orphan Drug status.
Promising T-cell Engager Results
VIR-5818 and VIR-5500 T-cell engagers showed promising early signs of clinical activity in colorectal and prostate cancer, respectively, with encouraging safety profiles and impressive PSA responses.
Strong Financial Position
The company has a cash runway extending into mid-2027, achieved by significantly reducing operating expenses and cash burn.
Significant Financial Improvements
R&D expenses decreased by approximately 30% year-over-year, and G&A expenses were reduced by 32% year-over-year. Net loss decreased by approximately 32% from the previous year.