Competitive ChallengesThe competitive landscape in inflammatory bowel disease is intense, with at least seven TL1A-targeting programs already in development.
Program DiscontinuationThe company has discontinued the SL-172154 program in HR-MDS/AML due to lack of significant overall survival benefits compared to historical treatments.
Workforce ReductionManagement has announced a major restructuring, including a 40% reduction in workforce, as part of a strategic pivot.