Regulatory Progress for Fabry Disease Program
Sangamo has aligned with the FDA on a clear regulatory pathway to accelerated approval for their Fabry disease program, reducing the time to potential approval by 3 years and avoiding an additional costly registrational study.
Pfizer Hemophilia A Program Milestone
Pfizer's Phase III AFFINE trial for hemophilia A met its primary endpoint with a significant decrease in total annualized bleeding rate, unlocking potential for $220 million in regulatory and commercial milestones for Sangamo.
Genentech Collaboration and Financial Boost
Sangamo signed a neurology epigenetic regulation and capsid delivery license agreement with Genentech, receiving $50 million in upfront license fees and milestone payments.
First IND Submission for Neurology Indication
Sangamo submitted its first IND application for a neurology indication, with plans for the clinical trial to start in the middle of 2025.