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Phathom Pharmaceuticals (PHAT)
NASDAQ:PHAT
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Phathom Pharmaceuticals (PHAT) AI Stock Analysis

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PHAT

Phathom Pharmaceuticals

(NASDAQ:PHAT)

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Neutral 51 (OpenAI - 4o)
Rating:51Neutral
Price Target:
$14.00
▲(3.40% Upside)
Phathom Pharmaceuticals' overall score reflects significant financial challenges, with ongoing losses and negative cash flows weighing heavily. Despite strong technical momentum and positive earnings call guidance, the negative valuation metrics and financial instability are major concerns. The company's reliance on external financing and potential supply disruptions also pose risks.
Positive Factors
Revenue Growth
Phathom's strong revenue growth indicates successful market penetration and product adoption, essential for long-term sustainability and expansion.
Product Exclusivity
Securing product exclusivity until 2032 provides a competitive edge, ensuring market protection and potential revenue stability over the long term.
Strategic Sales Focus
Focusing on gastroenterologists enhances market penetration and prescription growth, leveraging expertise to drive deeper engagement and adoption.
Negative Factors
Financial Instability
Ongoing financial instability, with high losses and reliance on external funding, poses risks to long-term viability and operational flexibility.
Negative Cash Flow
Negative cash flow challenges the company's ability to fund operations internally, increasing dependency on external financing and impacting growth potential.
Potential Supply Disruption
Potential supply disruptions could impact product availability and sales, affecting customer trust and long-term market position.

Phathom Pharmaceuticals (PHAT) vs. SPDR S&P 500 ETF (SPY)

Phathom Pharmaceuticals Business Overview & Revenue Model

Company DescriptionPhathom Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing treatments for gastrointestinal diseases. The company has the rights in the United States, Europe, and Canada to vonoprazan, a potassium-competitive acid blocker (P-CAB) that blocks acid secretion in the stomach. It is also developing vonoprazan, which is in Phase III clinical trials for the treatment of erosive gastroesophageal reflux disease; and in combination with antibiotics for the treatment of Helicobacter pylori infection. Phathom Pharmaceuticals, Inc. was incorporated in 2018 and is headquartered in Florham Park, New Jersey.
How the Company Makes MoneyPhathom Pharmaceuticals generates revenue primarily through the commercialization of its pharmaceutical products, particularly Vonoprazan, once it receives regulatory approval and gains market access. The company may also explore partnerships with larger pharmaceutical firms for co-development and distribution agreements, which can provide upfront payments, milestone payments, and royalties on sales. Additionally, the company's revenue stream could be bolstered by securing licensing agreements and collaborations that leverage its research capabilities and product pipeline, allowing it to monetize its intellectual property and scientific advancements.

Phathom Pharmaceuticals Earnings Call Summary

Earnings Call Date:Oct 30, 2025
(Q2-2025)
|
% Change Since: |
Next Earnings Date:Mar 03, 2026
Earnings Call Sentiment Positive
The earnings call reflects strong growth in prescription numbers and revenue, successful cost management, and a positive resolution regarding product exclusivity. However, there are potential challenges with supply disruptions and Medicare coverage. The strategic focus on gastroenterologists is expected to drive further growth.
Q2-2025 Updates
Positive Updates
Strong Prescription Growth
Over 580,000 VOQUEZNA prescriptions have been filled since launch, with a 49% growth in 14 weeks. In Q2, approximately 173,000 prescriptions were filled, marking a 36% growth over Q1.
Revenue and Cost Management
Reported $39.5 million in revenue for Q2, representing a 39% growth over Q1. Implemented cost savings initiatives mid-quarter, resulting in a $12 million reduction in Q2 non-GAAP OpEx compared to Q1.
Positive Exclusivity Resolution
Achieved a positive resolution to the citizens petition, securing exclusivity for VOQUEZNA tablets through May 2032, with potential extension to 2033.
Refocused Sales Strategy
Shifted sales focus to gastroenterologists, with 70% of prescriptions coming from GIs. This strategy is expected to drive deeper engagement and increase adoption.
Financial Stability
Ended the quarter with approximately $150 million in cash, with expectations to reach profitability by 2026 without additional equity financing.
Negative Updates
Potential Supply Disruption
Possible supply disruption in the VOQUEZNA triple pack due to clarithromycin tablets, though no commercial disruption experienced yet.
Medicare Market Challenges
Low percentage of Medicare patients achieve coverage, with many scripts ending up as cash pay through BlinkRx.
Company Guidance
During the Phathom Pharmaceuticals Second Quarter 2025 earnings call, the company reported significant growth and provided positive guidance for the year. Key metrics included a 39% increase in Q2 revenues to $39.5 million compared to Q1, driven by a 36% growth in VOQUEZNA prescriptions, totaling approximately 173,000 in the quarter. The company anticipates full-year 2025 revenues between $165 million and $175 million, exceeding analyst estimates. Phathom also highlighted its cost-saving initiatives, achieving a $12 million reduction in non-GAAP operating expenses from Q1. The company ended Q2 with $150 million in cash, expecting to reach profitability by 2026. The sales strategy pivot to focus on gastroenterologists was emphasized, with these specialists contributing 70% of VOQUEZNA prescriptions. Furthermore, Phathom plans to start a Phase II trial for eosinophilic esophagitis in Q4, with the potential for a future six-month pediatric exclusivity extension.

Phathom Pharmaceuticals Financial Statement Overview

Summary
Phathom Pharmaceuticals is facing significant financial challenges, with substantial net losses and negative cash flows. Despite revenue growth, the company has negative equity and relies heavily on financing activities, posing a risk if external funding becomes scarce.
Income Statement
42
Neutral
Phathom Pharmaceuticals has shown significant revenue growth, with TTM (Trailing-Twelve-Months) revenue increasing to $81.86 million from $55.25 million annually. However, the company is experiencing substantial losses, with a negative net profit margin and EBIT margin in both TTM and annual reports. The gross profit margin is strong at approximately 86.2% in TTM, but the net loss remains a concern, impacting the overall profitability.
Balance Sheet
35
Negative
The balance sheet indicates a negative stockholders' equity of $338.38 million, reflecting high liabilities compared to assets. Total debt has reduced, but the company still faces a high debt-to-equity ratio due to negative equity. This presents a risk of instability. The equity ratio is also negative, further emphasizing the financial leverage and instability concerns.
Cash Flow
40
Negative
Operating cash flow remains negative, with a worsening trend in TTM at -$282.68 million. Free cash flow also decreased, indicating potential cash flow challenges. However, the company has managed to maintain financing cash flows, which slightly offsets the negative operating cash flow impact. The operating cash flow to net income ratio reflects inefficiency in converting income to cash flow.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue114.04M55.25M682.00K0.000.000.00
Gross Profit99.11M47.28M515.00K-620.00K-521.00K-300.00K
EBITDA-259.55M-261.52M-159.05M-171.82M-134.56M-124.19M
Net Income-330.15M-334.33M-201.59M-223.01M-148.09M-133.32M
Balance Sheet
Total Assets250.22M378.32M413.84M164.81M189.43M295.11M
Cash, Cash Equivalents and Short-Term Investments149.57M297.26M381.39M155.38M183.26M287.50M
Total Debt574.50M554.95M139.03M97.07M91.34M49.02M
Total Liabilities656.05M631.90M486.60M239.62M117.28M100.84M
Stockholders Equity-405.83M-253.58M-72.76M-74.81M72.16M194.27M
Cash Flow
Free Cash Flow-274.63M-266.90M-139.21M-147.57M-148.94M-70.73M
Operating Cash Flow-274.69M-266.77M-137.58M-146.53M-148.62M-69.69M
Investing Cash Flow-164.00K-135.00K-1.63M-1.04M-328.00K-1.04M
Financing Cash Flow148.18M182.77M367.58M120.04M44.71M114.46M

Phathom Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Positive
Last Price13.54
Price Trends
50DMA
12.20
Positive
100DMA
10.76
Positive
200DMA
7.92
Positive
Market Momentum
MACD
0.55
Negative
RSI
59.03
Neutral
STOCH
61.68
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For PHAT, the sentiment is Positive. The current price of 13.54 is above the 20-day moving average (MA) of 12.76, above the 50-day MA of 12.20, and above the 200-day MA of 7.92, indicating a bullish trend. The MACD of 0.55 indicates Negative momentum. The RSI at 59.03 is Neutral, neither overbought nor oversold. The STOCH value of 61.68 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for PHAT.

Phathom Pharmaceuticals Risk Analysis

Phathom Pharmaceuticals disclosed 84 risk factors in its most recent earnings report. Phathom Pharmaceuticals reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Phathom Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
$1.36B-51.86%-37.09%58.96%
$1.27B-88.40%
$7.86B-0.30-43.30%2.27%22.53%-2.21%
$959.87M1049.81%7.85%
$883.73M-16.13-52.82%53.23%35.32%
$784.76M-9.28-31.09%11877.28%63.14%
$915.10M-5.9610.85%-1.41%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PHAT
Phathom Pharmaceuticals
13.53
-3.89
-22.33%
GERN
Geron
1.23
-2.92
-70.36%
ABUS
Arbutus Biopharma
4.61
0.67
17.01%
URGN
Urogen Pharma
19.78
6.76
51.92%
TSHA
Taysha Gene Therapies
5.01
3.14
167.91%
ZBIO
Zenas BioPharma, Inc.
28.01
7.01
33.38%

Phathom Pharmaceuticals Corporate Events

Executive/Board Changes
Phathom Pharmaceuticals Appoints New Chief Financial Officer
Neutral
Oct 6, 2025

On October 6, 2025, Phathom Pharmaceuticals appointed Sanjeev Narula as Chief Financial and Business Officer, succeeding Robert Breedlove as the principal financial officer. Mr. Narula’s extensive experience includes roles at Intra-Cellular Therapies, Viatris Inc., and Pfizer, bringing significant financial leadership to Phathom. His appointment is accompanied by a comprehensive employment agreement that outlines his compensation, severance benefits, and stock options, potentially impacting the company’s strategic financial management and stakeholder interests.

The most recent analyst rating on (PHAT) stock is a Buy with a $20.00 price target. To see the full list of analyst forecasts on Phathom Pharmaceuticals stock, see the PHAT Stock Forecast page.

Phathom Pharmaceuticals’ Earnings Call Highlights Growth and Challenges
Aug 13, 2025

Phathom Pharmaceuticals’ recent earnings call exuded a positive sentiment, underscored by robust growth in prescriptions and revenue, a strong financial standing, and effective cost-saving strategies. Despite these achievements, the company faces challenges such as potential supply disruptions and strategic shifts in sales focus.

Phathom Pharmaceuticals Reports Strong Q2 Growth
Aug 8, 2025

Phathom Pharmaceuticals, Inc. is a biopharmaceutical company specializing in the development and commercialization of innovative treatments for gastrointestinal diseases, with a focus on their flagship product, VOQUEZNA®.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 22, 2025