Revenue Growth and Financial Performance
NovoCure generated $605 million in net revenue for 2024, a 19% increase year-over-year, with a 21% increase in Q4 2024 compared to the same period in 2023. The company achieved a gross margin of 77% for the year, up from 75% in 2023, driven by improved US approval rates.
Expansion into New Indications
Received FDA approval for the treatment of second-line non-small cell lung cancer with Optune Lua. Achieved successful Phase 3 readouts for METIS (brain mets from non-small cell lung cancer) and PANOVA-3 (locally advanced pancreatic cancer), marking a pivotal expansion from a single indication to a multi-indication platform.
Clinical Trial Success
METIS trial met its primary endpoint with patients exhibiting 21.9 months median time to intracranial progression. PANOVA-3 trial demonstrated a median overall survival of 16.2 months, showing significant benefits in difficult-to-treat populations.
Product Development Milestones
Approved HFE arrays in the US and Japan, which are thinner, lighter, and more flexible, aiming to improve patient usage and expand market reach.