Positive Phase II Results for NTLA-2002
Unprecedented positive results from the Phase II study of NTLA-2002 for hereditary angioedema, showing potential for a functional cure with a simple onetime infusion.
FDA Clearance for MAGNITUDE-2 Study
FDA cleared the IND application for the Phase III trial of nex-z for hereditary ATTR amyloidosis with polyneuropathy, marking the fourth consecutive IND clearance within 30 days of submission.
Strong Financial Position
Intellia reported $944.7 million in cash and marketable securities as of September 30, 2024, with a financial runway expected to fund operations into late 2026.
Advancement in Gene Insertion Programs
Progress in in vivo gene insertion programs, particularly NTLA-3001 for alpha-1 antitrypsin deficiency, with plans to dose the first patient in the Phase I/II study by year-end.
Broad Enthusiasm for CRISPR-based Medicines
Progress in three active Phase III studies expected by year-end, indicating leadership in the field of in vivo CRISPR-based medicines.