NDA Submission for Paltusotine
Crinetics submitted its first NDA for paltusotine for the treatment and long-term maintenance of acromegaly, with FDA filing notification expected in December.
Strong Financial Position
Crinetics ended Q3 2024 with approximately $863 million in cash and investments, bolstered by a $575 million equity offering, resulting in $1.4 billion on a pro forma basis.
Development of Nonpeptide Drug Conjugates (NDCs)
Introduction of CRN09682, a first NDC candidate, designed to selectively target and kill tumor cells with promising preclinical results.
Advancement in Atumelnant Programs
Progress in atumelnant for congenital adrenal hyperplasia and Cushing's disease, with Phase III studies anticipated for 2025.
Global Expansion Initiatives
Establishing operations in Europe, including hiring a General Manager in Switzerland, and preparing for the commercialization of paltusotine in Europe.