Progress in ALPHA3 Trial for Large B-Cell Lymphoma
The pivotal Phase II ALPHA3 trial of cema-cel for large B-cell lymphoma is advancing, with 27 of the planned 50 sites activated, including 60% at community centers.
Breakthrough in Solid Tumor Treatment
ALLO-316 showed a confirmed response rate of 33% and best overall response rate of 50% in the Phase I TRAVERSE trial for renal cell carcinoma, earning RMAT designation from the FDA.
Innovative Dual CAR-T Approach for Autoimmune Diseases
ALLO-329, the first dual CD19 CD70 CAR, aims to reduce or eliminate the need for lymphodepleting chemotherapy, with IND filing expected in Q1 2025.
Strong Financial Position
Cash balance of $403.4 million as of Q3 2024, with cash runway extending into the second half of 2026.