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Sionna Therapeutics initiated with a Buy at TD Cowen

Sionna Therapeutics initiated with a Buy at TD Cowen

TD Cowen initiated coverage of Sionna Therapeutics (SION) with a Buy rating. Sionna’s pipeline of cystic fibrosis therapies directly target NBD1, which was previously thought to be “undruggable,” and in vitro and early clinical data suggest the company’s NBD1 drug candidates may improve or normalize CFTR function in combonations therapies. SION-719 and SION-451 are in Phase 1 trials with data due in the first half of this year and a Phase 2a proof of concept trial will start in the second half with data due in 2026, the analyst noted.

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