QT Imaging: 2nd blinded screening trial finds technology as effective as DBT

QT Imaging Holdings announces positive data regarding the diagnostic performance of QTI‘s Breast Acoustic CTTM Scans for mass detection from its second blinded multi-reader multi-case study. The study was published in Academic Radiology, online, in January 2024: A Multireader Multicase MRMC Receiver Operating Characteristic ROC Study Evaluating Noninferiority of Quantitative Transmission QT Ultrasound to Digital Breast Tomosynthesis DBT on Detection and Recall of Breast Lesions – Academic Radiology…Twenty-four breast radiologists participated in a study of 177 selected cases. The study found that QTI’s Breast Acoustic CTTM is similarly effective as digital breast tomosynthesis DBT , also known as 3D mammography, in that the area under receiver operating characteristic curve AUC was statistically non-inferior for QTI scan compared with DBT for the AUC difference margin of -0.05. This means that QTI technology is non-inferior to DBT in the detection of breast lesions as a whole, with high specificity in determining benign cysts and thus decreasing benign recall rates. Statistical analysis was performed by Dr. Yulei Jiang from the Department of Radiology of the University of Chicago…”We are encouraged by the consistent high performance of QTI’s technology, especially in women with dense breasts. Along with the previously published results and from comparison of QTI’s scans with mammography, these trial results will be valuable for our planned FDA submission for a screening indication in younger women identified with above-average risk for developing breast cancer and who have not yet reached the age for conventional mammography-based screening,” said Dr. Bilal Malik, Chief Science Officer. The results of the study comparing QTI’s technology performance with mammography were published in Academic Radiology, in December 2020: An Exploratory Multi-reader, Multi-case Study Comparing Transmission Ultrasound to Mammography on Recall Rates and Detection Rates for Breast Cancer Lesions – Academic Radiology