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ProMIS Neurosciences presents preclinical data on ABO at AAIC

ProMIS Neurosciences presents preclinical data on ABO at AAIC

ProMIS Neurosciences presented preclinical data at the 2024 Alzheimer’s Association International Conference, AAIC, that further supports the potential therapeutic advantage of the Company’s novel approach to optimization of an Alzheimer’s disease vaccine for maximum targeting of toxic amyloid-beta oligomers, ABO. The results from the study showed that vaccination with ABO-restricted conformational B cell epitopes produced strong antibody responses with no measurable pro-inflammatory T cell responses against AB. Importantly, immunization with epitope 301, the target of PMN310, alone was sufficient to produce maximal reactivity against brain ABO.

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