PainReform cut to Hold at Maxim amid ‘changed’ market dynamics
The Fly

PainReform cut to Hold at Maxim amid ‘changed’ market dynamics

As previously reported, Maxim analyst Naz Rahman downgraded PainReform (PRFX) to Hold from Buy. The company is developing PRF-110 to treat post-operative pain and compete in the market with Exparel and Zynrelef, but market dynamics have recently changed, with a generic for Exparel – the market leader – having been approved in July 2024 and impacting the market opportunity for PainReform and its operational ramifications, the analyst tells investors in a research note. Maxim adds that PainReform is on pace to complete its Phase 3 bunionectomy study in Q4, noting however that the company still needs to complete a soft tissue study and potentially a third study for the safety database, and the firm believes that additional capital will likely be required to complete these studies.

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