Orchestra BioMed announces AVIM therapy program presentations

Orchestra BioMed (OBIO) announced two presentations at the 2024 Innovation in Cardiology Intervention meeting in Tel Aviv, Israel. The presentations will provide insights on the ongoing BACKBEAT global pivotal study, as well as an overview of the novel mechanism of action of AVIM therapy and supporting clinical evidence for the treatment of uncontrolled hypertension in patients indicated for a dual-chamber pacemaker. The presentations will be part of a broad scientific program of important developments in cardiology, in a session focused on “Device-Based Hypertension Treatment.” Insights into the BACKBEAT IDE Study, presented by Avi Fischer, M.D., Senior Vice President of Medical Affairs and Innovation, Orchestra Biomed: Dr. Fischer’s presentation will focus on the unmet medical need in patients who are indicated for a pacemaker and also have uncontrolled hypertension despite the use of antihypertensive medication. This group of patients is the target population for the BACKBEAT global pivotal study, which reflects the increased risks associated with elevated systolic blood pressure in older comorbid patients. AVIM Mechanism of Action & Supporting Clinical Evidence, presented by Andrea Russo, M.D., FACC, FHRS, FAHA, Professor of Medicine, Cooper Medical School of Rowan University, Academic Chief, Division of Cardiology, Director, Electrophysiology and Arrhythmia Services, Cooper University Hospital, and Co-Principal Investigator of the BACKBEAT study: Dr. Russo’s session will delve into the unique mechanism of action of the AVIM therapy and robust body of supporting clinical data. Dr. Russo will detail how AVIM therapy is designed to modulate the autonomic nervous system to immediately, substantially and persistently reduce blood pressure, as demonstrated in the MODERATO I and II pilot studies.