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OnKure Therapeutics initiated with an Outperform at Leerink
The Fly

OnKure Therapeutics initiated with an Outperform at Leerink

Leerink analyst Andrew Berens initiated coverage of OnKure Therapeutics (OKUR) with an Outperform rating and $33 price target The firm notes OnKure is leveraging an expertise in targeted drug discovery to develop a platform of highly targeted PI3Kalpha agents that are more potent at relevant oncogenic mutations, while sparing normal tissues. Leerink views the company’s lead asset OKI-219 as a potential blockbuster+ agent, targeting H1047R mutations in HR+ breast cancer. Its peak sales for ‘219 in breast cancer are $1.4B, which represents $30/share in the firm’s model.

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