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Kazia Therapeutics launches trial of paxalisib/immunotherapy combination
The Fly

Kazia Therapeutics launches trial of paxalisib/immunotherapy combination

Kazia Therapeutics (KZIA) is pleased to announce the regulatory approval and launch of a clinical trial evaluating the combination of paxalisib and immunotherapy in patients with advanced breast cancer. This novel treatment combination offers what is believed to be a unique approach to targeting this highly aggressive and treatment-resistant type of breast cancer. The ABC-Pax study is the first known trial conducted to assess the safety and efficacy of paxalisib in combination with KEYTRUDA or LYNPARZA in women with triple negative breast cancer. ABC-Pax is a multi-centre, open-label phase 1b study that will enroll 24 patients from top cancer centres in Queensland, Australia and patients will receive the combination therapy for up to 12 months.

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