Jaguar submits abstract for study of impact of diarrhea from cancer therapies

Jaguar Health announced that a late-breaking abstract evaluating the incidence, severity and management of diarrhea from targeted therapies with or without standard chemotherapy in the cohort of adult patients with breast cancer in the placebo group of the OnTarget phase 3 study recently conducted by Jaguar family company Napo Pharmaceuticals, was submitted by the study’s primary investigators to a relevant oncology conference for consideration for a presentation. In this study 142 patients with solid tumors received placebo tablets and nearly 75 of them were patients with breast cancer receiving targeted therapies with or without standard chemotherapy. These findings were collected from patient reported outcomes provided by the patients using digital applications for their gastrointestinal signs and symptoms. Napo is continuing the analysis of data from the OnTarget trial, with plans for further discussions with the FDA. The natural history from the placebo group of patients with breast cancer provides further insights into cancer therapy dose modifications necessitated due to cancer therapy-related diarrhea.