IGC Pharma announced enrollment of patients at the Baycrest Academy for Research and Education in Toronto, Ontario, Canada, as part of the Company’s ongoing Phase 2 trial investigating IGC-AD1 as a treatment for agitation in Alzheimer’s dementia. Agitation affects between 40-80% of Alzheimer’s patients and is a major driver of long-term hospitalization, increased mortality, and higher use of medication. IGC-AD1 is a partial CB1 receptor agonist with anti-neuroinflammatory properties and acts as an inflammasome inhibitor, addressing key pathways involved in the neuroinflammation, oxidative stress, and neurotransmitter imbalances that are implicated with agitation in Alzheimer’s disease pathology. IGC Pharma have 12 U.S. trial sites under contract and is on target to enroll additional sites in Canada to increase population diversity. The trial will enroll 164 patients with one half, the treated group, receiving IGC-AD1, and the other half, the control group, receiving a placebo.
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