Dyne Therapeutics reports Q4 EPS (88c), consensus (91c)

Cash, cash equivalents and marketable securities were $642.3M as of December 31, 2024. During Q1, the company received net proceeds of approximately $140.6M from the sale of stock through its at-the-market offering program. The company expects that its cash, cash equivalents and marketable securities as of December 31, 2024, together with the net proceeds from the Q1 2025 at-the-market offering, will be sufficient to fund its operations at least into the second half of 2026.”Our most recent clinical data for DYNE-101 from the ACHIEVE trial in DM1 patients showed substantial functional benefit, including the reversal of disease progression and improvement across a range of clinical measures, as well as a favorable safety profile. We believe that the compelling benefits seen with DYNE-101 result from addressing the underlying biology of this devastating neuromuscular disease through meaningful splicing correction,” said CEO John Cox. “With these results in hand, we are moving rapidly to initiate a Registrational Expansion Cohort to support a potential submission for U.S. Accelerated Approval. Furthermore, in DMD, we expect data from the ongoing DELIVER trial of DYNE-251 in late 2025 to support a potential submission for U.S. Accelerated Approval in early 2026, giving us the transformational opportunity to launch two important therapies in 2027.”