Cassava Sciences reports Q4 EPS (57c) vs (50c) last year

“Cassava is preparing to report the topline results of the now-discontinued REFOCUS-ALZ, the second Phase 3 study of simufilam in Alzheimer’s disease, in late first-quarter/early second-quarter 2025. We intend to evaluate the next steps for simufilam in Alzheimer’s disease after reviewing the REFOCUS-ALZ results in conjunction with the results of the RETHINK-ALZ study, reported in November 2024, which did not meet the prespecified co-primary endpoints,” said Rick Barry, President and Chief Executive Officer at Cassava. “We are pleased to have entered a licensing agreement with Yale University which allows us to build on the promising research of Angelique Bordey, PhD, Professor of Neurosurgery and Vice Chair of Research, Neurosurgery at Yale, to explore simufilam’s potential as a treatment for TSC-related seizures. We look forward to updating investors on our progress in the coming months.”