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Carisma Therapeutics downgraded to In Line from Outperform at Evercore ISI
The Fly

Carisma Therapeutics downgraded to In Line from Outperform at Evercore ISI

Evercore ISI downgraded Carisma Therapeutics (CARM) to In Line from Outperform with a price target of 70c, down from $4. With its second major pipeline shift this year, Carisma is focusing on in vivo CAR-M for liver fibrosis while collaborating with partner Moderna (MRNA) on oncology and autoimmune disease, but with a line of sight to an IND 2026, Carisma is now “back in preclinical stage for its wholly owned pipeline,” the analyst tells investors. Given that the company is a couple of years away from a meaningful data catalyst, and in light of the cash runway, the firm reduced its price target and rating.

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