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Cara Therapeutics downgraded to Hold on study failure at Canaccord

Cara Therapeutics downgraded to Hold on study failure at Canaccord

Canaccord last night downgraded Cara Therapeutics to Hold from Buy with a price target of $1, down from $10. The company announced that oral difelikefalin did not demonstrate meaningful clinical benefit versus placebo at any dose as part of the dose-finding Part A of its KOURAGE Phase 3 study in notalgia paresthetica, the analyst tells investors in a research note. The firm is “somewhat surprised by this clearly negative outcome.” It finds it difficult to predict what the results of any upcoming strategic initiatives might be.

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