BioAge Labs to present preclinical data for azelaprag

BioAge Labs (BIOA) announced that it will present new preclinical data for its lead product candidate azelaprag, an orally available small molecule agonist of the apelin receptor APJ. The data will be presented at ObesityWeek 2024, held in San Antonio from November 2-6, 2024. In their two presentations, BioAge CMO and EVP Research Paul Rubin, MD, and VP Translational Aging Biology Yan Wang, PhD, will present data demonstrating that in mice on a high-fat diet, azelaprag increased weight loss and improved body composition in combination with semaglutide, tirzepatide, the oral GLP-1 receptor agonist danuglipron, or the oral CB1 inverse agonist rimonabant. These studies demonstrate the potential of azelaprag to be complementary to a range of oral appetite suppression mechanisms for the treatment of obesity.