Artelo Biosciences presents preclinical data on ART26.12

Artelo Biosciences announced Professor Saoirse O’Sullivan, Vice President of Translational Sciences at Artelo, presented preclinical data related to ART26.12, Artelo’s novel fatty acid binding protein 5 inhibitor at the 34th Annual International Cannabinoid Research Society Symposium being held June 30 to July 5, 2024 in Salamanca, Spain. The presentation entitled, “ART26.12, a Novel Fatty Acid-Binding Protein 5 Inhibitor, Shows Efficacy in Breast Cancer-Induced Bone Pain,” highlights the effectiveness of ART26.12 in reducing pain behaviors induced by breast cancer in preclinical studies. This new data is from the fourth in a series of preclinical pain models that demonstrated similar activity with ART26.12. Specifically, effective doses and plasma exposures in the breast cancer bone pain study are consistent with previously published data of ART26.12 in oxaliplatin-induced peripheral neuropathy. “ART26.12 continues to deliver positive preclinical efficacy data to support its development as a novel non-opioid, non-steroidal analgesic treatment,” stated Professor Saoirse O’Sullivan, Vice President of Translational Sciences at Artelo. “We continue to be impressed with the consistent activity and efficacious dose levels of ART26.12 in multiple animal models of pain and painful neuropathies, whether caused by cancer, diabetes, or multiple chemotherapies. We look forward to initiating human trials with ART26.12 subject to Artelo’s Investigational New Drug application acceptance by the U.S. Food and Drug Administration.”