Artelo Biosciences (ARTL) announced the completed safety review of the first cohort of eight healthy volunteers in the Company’s Phase 1 study of ART26.12. Progression to the next cohort marks a major milestone in the development of Fatty Acid Binding Protein, FABP, inhibitors as a novel treatment approach for a large number of potential indications. “We are pleased to report on the progress with ART26.12, our lead FABP inhibitor,” said Gregory D. Gorgas, President and Chief Executive Officer of Artelo Biosciences. “Based on the encouraging safety profile of ART26.12 in preclinical studies, we look forward to learning from the initial safety, pharmacokinetic, and biomarker data from this ongoing human study, which is expected to be completed during the first half of 2025. As the leading company pursuing FABP inhibition, we are committed to building on the unique, lipid-modulating mechanism of FABP inhibition to address the unmet needs of patients reliant on medicines that are often ineffective and intolerable. ART26.12 is the first clinical stage candidate drug from our extensive FABP inhibitor platform.”
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