AC Immune announces interim safety, tolerability data from ABATE Phase 1b/2

AC Immune (ACIU) SA announced interim safety and tolerability data from the ABATE Phase 1b/2 trial of ACI-24.060 in individuals living with Down syndrome, DS. Targeting toxic forms of amyloid beta, ACI-24.060 is an active immunotherapy covering Abeta 1-15. The interim analysis was based on data from the first two cohorts of individuals with DS receiving low-dose and mid-dose ACI-24.060. DS subjects in the interim analysis have been treated for up to one year, with no serious adverse events related to the study drug and no case of amyloid-related imaging abnormalities, ARIA, observed in this study population.