Tiziana Life Sciences ( (TLSA) ) has issued an announcement.
On April 2, 2025, Tiziana Life Sciences announced the commencement of dosing at Johns Hopkins University for its Phase 2 trial of intranasal foralumab, aimed at treating non-active Secondary Progressive Multiple Sclerosis (na-SPMS). This trial, which also includes Brigham and Women’s Hospital and Yale Medical Center, seeks to evaluate the safety and efficacy of foralumab, a promising treatment for na-SPMS, a condition with limited current treatment options. The trial’s expansion to a third site underscores Tiziana’s commitment to advancing innovative treatments for neurodegenerative diseases, with the blinded portion expected to conclude by the end of 2025, followed by an open-label extension period.
More about Tiziana Life Sciences
Tiziana Life Sciences is a clinical-stage biopharmaceutical company focused on developing breakthrough therapies using transformational drug delivery technologies. Their lead candidate, intranasal foralumab, is a fully human anti-CD3 monoclonal antibody that has shown a favorable safety profile and clinical response. The company’s innovative nasal delivery approach aims to improve efficacy, safety, and tolerability compared to traditional intravenous delivery methods.
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