Silence Therapeutics’ Divesiran Shows Promise in PV Study

Silence Therapeutics (SLN) has released an update.

Silence Therapeutics has reported promising outcomes from its Phase 1 SANRECO study of divesiran in polycythemia vera patients, showing elimination of phlebotomy requirements in well-controlled individuals and a good safety profile. The data supports the progression of divesiran into Phase 2 trials. With its potential as the first siRNA therapy for this condition, divesiran demonstrates sustained reduction in hematocrit and favorable effects on iron metabolism indicators.

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