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Amphastar’s Earnings Call: Growth Amid Challenges

Amphastar’s Earnings Call: Growth Amid Challenges

Amphastar Pharmaceuticals Inc ((AMPH)) has held its Q4 earnings call. Read on for the main highlights of the call.

Amphastar Pharmaceuticals Inc. recently conducted its earnings call, revealing a balanced sentiment marked by significant revenue growth and strategic partnerships, particularly for its key products Primatene MIST and BAQSIMI. Despite these positive developments, the company faces challenges such as declining glucagon sales, reduced gross margins, and increased competition. Optimism in pipeline developments is tempered by these competitive and margin pressures.

Strong Revenue Growth

Amphastar Pharmaceuticals reported impressive revenue figures for fiscal year 2024, achieving $732 million, a 14% increase from the previous year. The fourth quarter alone saw revenues of $186 million, marking a 5% year-over-year growth. This growth underscores the company’s robust performance and strategic initiatives.

Primatene MIST Sales Milestone

Primatene MIST, one of Amphastar’s cornerstone products, reached a significant milestone with annual sales hitting $102 million. This represents a 14% increase from 2023, surpassing the $100 million goal set three years ago, showcasing the product’s strong market presence and demand.

Strategic Partnership with MannKind

Amphastar has entered a new strategic partnership with MannKind to promote BAQSIMI, a move aimed at expanding its sales reach and strengthening its position in the diabetes care market. This collaboration is expected to enhance BAQSIMI’s market reach and contribute positively to the company’s growth.

Pipeline and Regulatory Developments

The company remains optimistic about its pipeline, anticipating the potential approval of four key products in 2025, including AMP-002, AMP-007, AMP-015, and AMP-018. These developments mark significant progress in Amphastar’s regulatory pipeline and future growth prospects.

Glucagon Sales Decline

Amphastar reported a 5% decline in annual glucagon sales, attributed to increasing competitive pressures and a market shift towards ready-to-use products like BAQSIMI. This decline highlights the challenges the company faces in maintaining its market share.

Decreased Gross Margins

The company’s gross margins decreased to 46.5% in Q4 2024 from 54% in Q4 2023. This decline is primarily due to BAQSIMI sales recorded net of Lilly’s expenses and higher labor and component costs, impacting the company’s profitability.

Increased Competition Impact

Amphastar’s epinephrine sales have decreased due to increased competition, with hospital and clinic use products facing heightened competitive pressures. This increased competition poses a challenge to the company’s market position.

Delayed Product Approvals

The approval of AMP-002 has faced delays since Q2 2023, and AMP-004 (insulin aspart) approval is unlikely until late 2025. These delays in product approvals could impact the company’s growth trajectory and market expansion plans.

Forward-Looking Guidance

Amphastar Pharmaceuticals provided guidance for 2025, projecting high single-digit growth for Primatene MIST, supported by an expanded physician sampling program. BAQSIMI is expected to see high single-digit unit growth following a price increase. The company anticipates launching two new products in 2025, with four key products under regulatory review. Despite these positive forecasts, Amphastar projects flat sales for 2025, with a return to double-digit growth in 2026, as it navigates pricing pressures and competition. Gross margins are expected to decrease, while R&D and capital expenditures will rise to expand manufacturing capacity and advance the insulin portfolio.

In summary, Amphastar Pharmaceuticals Inc.’s earnings call reflects a balanced sentiment with significant revenue growth and strategic partnerships, particularly for Primatene MIST and BAQSIMI. However, challenges such as declining glucagon sales, reduced gross margins, and increased competition pose hurdles. The company’s forward-looking guidance highlights optimism in pipeline developments and strategic initiatives, aiming for a return to double-digit growth in 2026.

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