Drug Safety ConcernsBarzo’s on-target neutropenia, hair discoloration, and other side effects could affect utilization by many patients/clinicians.
Investor SentimentShort Interest is at 12.7% of the float, which may indicate a level of pessimism among some investors.
Market CompetitionPotential approvals for Xolair biosimilars, Dupixent, and remibrutinib will likely confine barzo exclusively to 2L+, which is a smaller opportunity than CLDX projected.